LP266961-4
Cells.CD19+CD27+IgD+IgM+
Active
Description
The B lymphocytes that are CD27+IgD+IgM+, also known as non-switched memory B cells, are lymphocytes whose function and origin in normal patients is unresolved. They are described as non-switched because they are IgD+IgM+ and as memory cells because they are CD27+. This subset of B cells has been found to be reduced in patients with systemic lupus erythematosus (SLE). Increased levels of autoantibodies associated with SLE including ANA, anti-dsDNA and anti-ENA Ab correlate with a decreased level of CD27+IgD+IgM+ B lymphocytes. Studies have also shown that CD27+IgD+IgM+ B lymphocytes exhibit increased auto-reactivity and activation functionality. The level of CD27+IgD+IgM+ B lymphocytes remains reduced in patients with SLE even when they are in remission. PMID: 20525218 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- CD19+CD27+IgD+IgM+ cells
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-04-26
- Construct for LOINC Short Name
- CD19+CD27+IgD+IgM+ cells
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP266961-4
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| it-IT | Italian (Italy) | Cellule.CD19+CD27+IgD+IgM+ Synonyms: Cellule CD19+CD27+IgD+IgM+ |
| zh-CN | Chinese (China) | 细胞.CD19+CD27+IgD+IgM+ |
| es-ES | Spanish (Spain) | Células CD19+CD27+IgD+IgM+ |
| pl-PL | Polish (Poland) | Komórki.CD19+CD27+IgD+IgM+ Synonyms: Komórki CD19+CD27+IgD+IgM+ |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright