LP267187-5
Porcine reproductive and respiratory syndrome virus Ab.IgA+IgM
Active
Description
Veterinary medicine:
Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped, positive-sense, single-stranded RNA virus of the Afteriviridae family. PMID: 26984724 PRRSV was first identified in North America in the 1980s. Another genotype of PRRSV spread through Europe from 1990 to 1992. The two genotypes vary from one another by 40% and have since spread all over the world. PMID: 12967485 Sus scrofa is the only species of pig that is a natural host to PRRSV. Symptoms of PRRSV in adult pigs include reduced appetite, fever, premature farrowing and abortion, death in up to 10% or more of sows, loss of balance, circling, and falling to one side. Symptoms of PRRSV in litters include stillborn pigs, high pre-weaning mortality, mummified pigs, variable sized weak-born pigs, and edema around the eyes. In weaned pigs, symptoms of PRRSV include loss of appetite and lethargy, obvious failure to thrive, labored or rapid breathing and/or respiratory distress, blotchy reddening of the skin, and rough hair coats. PRRSV exhibits a tropism for macrophages, lungs, and lymphoid tissue during acute infection, and persists in the tonsils and lung macrophages. The destruction of macrophages impacts cellular immunity and damages mucosal surfaces. Diagnosis of PRRSV can be determined by cell culture, reverse transcriptase polymerase chain reaction (RT-PCR), enzyme-linked immunosorbent assay (ELISA), and indirect staining of a pre-prepared monolayer of infected cells (IPMA and IFA). IgM to PRRSV can be detected in pigs within 7 days of infection and IgG to PRRS can be detected within 14 days of infection.http://www.oie.int/fileadmin/Home/eng/Our_scientific_expertise/docs/pdf/PRRS_guide_web_bulletin.pdf Measuring IgA and IgM against PRRSV in piglets can determine that the infection is active, since IgA and IgM do not cross the placenta. IgG to PRRSV in piglets could indicate active infection, or antibodies that were passed from the sow to the piglet since IgG does cross the placenta. http://www.nationalhogfarmer.com/animal-health/building-better-mouse-trap-new-prrsv-oral-fluid-igm-iga-elisa
Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Porcine reproductive and respiratory syndrome virus Ab.IgA+IgM
- Part Display Name
- Porcine reproductive and respiratory syndrome virus IgA and IgM Ab
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-05-04
- Construct for LOINC Short Name
- PRRSV virus IgA+IgM
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Anticuerpos IgA+IgM específicos del virus del síndrome respiratorio y reproductivo porcino (PRRSV) |
| it-IT | Italian (Italy) | Virus sindrome respiratoria e riproduttiva dei suini Ab.IgA+IgM Synonyms: Virus PRRS Ab.IgA+IgM |
| zh-CN | Chinese (China) | 猪生殖与呼吸综合征病毒抗体.IgA+IgM Synonyms: 猪生殖与呼吸综合征病毒（PRRSV、 |
| pl-PL | Polish (Poland) | Wirus zespołu rozrodczo-oddechowego świń Ab.IgA+IgM Synonyms: Przeciwciała IgA oraz IgM do wirusa zespołu rozrodco-oddechowego świń |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://