LP267192-5
Haemophilus parasuis serotype
Active
Description
Veterinary medicine:
Haemophilus parasuis is a gram-negative bacterium that was first identified in 1992 and infects the upper respiratory tract of pigs. It causes worldwide systemic disease in pigs and is also known as Glässer's disease. Symptoms of severe disease include arthritis, meningitis, polyserositis, septicemia, and pneumonia. H parasuis is the primary cause of death in nursery herds and the third highest in finishing herds in the United States. Knowing the serotype of H parasuis infecting a herd helps to guide vaccination programs and prevent future outbreaks. Fifteen serovars were identified in 1992 using gel immunodiffusion (GID). Indirect hemagglutination (IHA) replaced GID as the test of choice and improved the percent of typable serovars from 60% to 80%. However, IHA has its own issues which include difficulties in obtaining specific antisera, variation in the growth rates between isolates, and very few laboratories perform the assay which is time-consuming, expensive and requires a pure culture. More recently a multiplex polymerase chain reaction (mPCR) assay has been developed that offers rapid and more accurate serovar identification. It uses the highly genetically variable capsule loci of the 15 serovars as the targets. Serovars 5 and 12 are indistinguishable by this method, suggesting that the difference in gene expression of the two is too subtle to detect, or that the serovars are in fact the same and an artifact of IHA typing antibodies. The virulence of the different serovars are reported to differ significantly, and mPCR results are able to accurately distinguish them and determine if multiple serovars are present in a sample. The rapid identification of serovars during an outbreak facilitate the availability of prophylactic vaccination. PMID: 26424843
Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Haemophilus parasuis serotype
- Part Display Name
- Haemophilus parasuis serotype
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-05-04
- Construct for LOINC Short Name
- H parasuis serotype
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| fr-FR | French (France) | Haemophilus parasuis sérotype |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://