Version 2.80

Description

Regulatory T-cells (Tregs) are a subset of CD4+ T-cells that provide protection from excess inflammation and tissue damage that would result from untethered immune responses directed against self, dietary, or environmental antigens. Tregs are characterized and dependent upon the expression of lineage-specific transcription factor Foxp3 and high levels of interleukin-2 (IL2) receptor alpha-chain (CD25). Tregs require the expression of CD25 for their differentiation and proliferative fitness and are dependent on IL2 signaling for their maintenance. Tregs suppress immune-mediated inflammation that is associated with autoimmune and auto-inflammatory disorders, allergies, acute and chronic infections, and cancer. Associations of Tregs with disease has prompted investigations into the manipulation of Tregs for therapeutic purposes. PMID: 27590281 Source: Regenstrief LOINC

Basic Part Properties

Part Name
T-cell regulatory subsets panel
Part Display Name
T-cell regulatory (Treg) subsets panel
Part Type
Component (Describes the core component or analyte measured)
Created On
2018-08-14
Construct for LOINC Short Name
T-cell regulatory subsets Pnl

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP268346-6

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de subclases de Células T reguladoras
it-IT Italian (Italy) Linfocita T regolatore, subset panel
Synonyms: Panel subset linfocita T regolatore (Treg)
zh-CN Chinese (China) T-细胞调节亚群组套
Synonyms: T-细胞（T细胞）调节亚群（子群、子集）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）
el-GR Greek (Greece) Πίνακας υποομάδας ρυθμιστικών Τ-κυττάρων
Synonyms: Πίνακας υποομάδας ρυθμιστικών Τ-κυττάρων