LP268351-6
BAFF-R Cells
Active
Description
B cell-activating factor (BAFF) is an immunomodulatory cytokine that advances the survival of B cells, the class switch recombination of heavy-chains, and can also activate T-cells. BAFF-R is the BAFF cell surface receptor and is present on the majority of B cells and a subset of T cells in the circulation. BAFF and BAFF-R normally play a role in B- and T- cell development and regulating humoral immunity, but in pathological conditions, may promote the survival of malignant B cells. The expression of BAFF-R has been associated with 78% of lymphoproliferative disorders including follicular lymphoma, marginal zone lymphoma, chronic lymphocytic leukemia, hairy cell leukemia, and diffuse large B-cell lymphoma, but not others such as precursor B lymphoblastic lymphoma, Burkitt lymphoma, and nodular lymphocyte-predominant Hodgkin lymphoma. In addition, BAFF-R is not a marker for classical Hodgkin lymphoma and T-cell lymphomas. PMID: 16226112 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- BAFF-R Cells
- Part Display Name
- BAFF-R cells
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-08-14
- Construct for LOINC Short Name
- BAFF-R cells
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Células BAFF-R |
| zh-CN | Chinese (China) | BAFF-R 细胞 Synonyms: BAFF 受体细胞; |
| it-IT | Italian (Italy) | BAFF-R, cellule Synonyms: Cellule BAFF-R |
| fr-FR | French (France) | BAFF-R |
| pl-PL | Polish (Poland) | Komórki posiadające receptor BAFF |
| el-GR | Greek (Greece) | Κύτταρα BAFF-R Synonyms: Κύτταρα BAFF-R |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://