Version 2.78

Description

A monoclonal band (M-spike, monoclonal protein isotype) is often found in patients with monoclonal gammopathies. Following protein electrophoresis, immunofixation is used to identify the immunoglobulin heavy chain and/or light chain. Monoclonal peaks greater than 3 g/dL and IgG or IgA are seen in patients with Multiple Myeloma (MM). A monoclonal peak greater than 3 g/dL and IgM is seen in patients with macroglobulinemia. An alternate methodology for identifying the monoclonal protein isotype is MALDI-TOF, in which known information regarding the unique mass of each isotype is used to determine and quantify the isotype present in the patient sample based on the mass spectra generated from the sample. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Protein.monoclonal isotype
Part Type
Component (Describes the core component or analyte measured)
Created On
2018-09-30
Construct for LOINC Short Name
M Protein isotype

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP269335-8

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 蛋白质.单克隆同种型
Synonyms: 蛋白质(蛋白).单克隆同种型;单克隆同种型蛋白质(蛋白)
es-ES Spanish (Spain) Isotipo de proteína monoclonal
it-IT Italian (Italy) Proteina.isotipo monoclonale
nl-NL Dutch (Netherlands) eiwit.monoklonaal isotype
pl-PL Polish (Poland) Izotyp białka monoklonalnego