Version 2.78

Descriptions

Linoleic acid (LA) is an unsaturated omega-6 fatty acid. It is a colorless liquid at room temperature. In physiological literature, it is called 18:2(n-6). Chemically, linoleic acid is a carboxylic acid with an 18-carbon chain and two cis double bonds; the first double bond is located at the sixth carbon from the omega end.

Linoleic acid is one of two essential fatty acids that humans and other animals must ingest for good health because the body requires them for various biological processes, but can not synthesize them from other food components. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Arachidonate (AA) is an essential polyunsaturated omega-6 fatty acid that is produced from dietary linoleic acid. AA is located in human fat, liver, brain, and glandular organs and is a mediator of inflammation. The AA within the phospholipids of cell membranes is the surface where the production of a number of biologically active compounds occurs. A few of the compounds produced includes prostaglandins, thromboxanes, and leukotrienes which regulate processes including platelet aggregation, blood clotting, smooth muscle contraction, leukocyte chemotaxis, inflammatory cytokine production, and immune function.[PubChem: 444899] AA is released from the cell membrane when acted upon by phospholipases and then metabolized by cyclooxygenase (COX) producing the prostanoids prostaglandin and thromboxane A2, which can stimulate or mitigate inflammation. PMID: 21508345 One of the benefits of the Omega-3 fatty acids for patients with inflammatory disease is believed to be their selective modification of the metabolism of AA by the omega-3 fatty acids that results in a reduced amount of inflammation. PMID: 23371504 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Arachidonate (C20:4w6)+Linoleate (C18:2w6)
Part Type
Component (Describes the core component or analyte measured)
Created On
2018-10-22
Construct for LOINC Short Name
AA+Linoleate

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP269768-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 花生四烯酸+亚油酸
es-ES Spanish (Spain) Araquinodato + Linoleato
it-IT Italian (Italy) Arachidonato+Linoleato
Synonyms: Arachidonato (C20:4w6)+Linoleato (C18:2w6)