LP28852-9
Estrogen+Progesterone receptor
Active
Description
Estrogen receptors (ER) are cellular proteins that bind estrogens with a high affinity and specificity. They are a necessary component for estrogen-mediated cellular activity. The presence of progesterone receptors (PR) demonstrates an active ER mechanism for the induction of PR expression. Immunohistochemical staining permits the detection and localization of ER/PR within sections from formalin-fixed, paraffin-embedded tissue.
Clinical utilities for the measurement of ER/PR include patient prognosis and patient response to adjuvant endocrine therapy. Individuals with receptor-positive tumors generally have a better prognosis, as indicated by a longer interval to disease recurrence and a longer overall survival, than patients with receptor-negative tumors. Studies have also shown that the determination of receptor status by immunohistochemistry may be useful in predicting patient response to hormonal therapy.
Source: LOINC partner 1
Basic Part Properties
- Part Name
- Estrogen+Progesterone receptor
- Part Display Name
- Estrogen+Progesterone receptor
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2002-06-17
- Construct for LOINC Short Name
- ERA+PGRA
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 雌激素+孕酮受体 Synonyms: ERA+PGRA; |
| fr-CA | French (Canada) | Oestrogène+Récepteur progestérone |
| et-EE | Estonian (Estonia) | Östrogeeni + progesterooni retseptor |
| es-ES | Spanish (Spain) | Receptor de Estrógeno+Progesterona |
| it-IT | Italian (Italy) | Estrogeno+Progesterone, recettore Synonyms: Recettore estrogeno+progesterone |
| tr-TR | Turkish (Turkey) | Östrojen+Progesteron reseptörü |
| ru-RU | Russian (Russian Federation) | Эстроген+Прогестерон рецептор |
| nl-NL | Dutch (Netherlands) | oestrogeen + progesteronreceptor |
| fr-BE | French (Belgium) | Récepteur Œstrogènes+ progestérone Synonyms: Récepteurs stéroides |
| fr-FR | French (France) | Estrogènes+progestérone récepteurs |
| pl-PL | Polish (Poland) | Estrogen+Progesteron receptor Synonyms: Receptor estrogenowy i progesteronowy |
| el-GR | Greek (Greece) | Υποδοχέας οιστρογόνων+προγεστερόνης Synonyms: Υποδοχέας οιστρογόνων+προγεστερόνης |
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