Version 2.77

Description

Estrogen receptors (ER) are cellular proteins that bind estrogens with a high affinity and specificity. They are a necessary component for estrogen-mediated cellular activity. The presence of progesterone receptors (PR) demonstrates an active ER mechanism for the induction of PR expression. Immunohistochemical staining permits the detection and localization of ER/PR within sections from formalin-fixed, paraffin-embedded tissue.

Clinical utilities for the measurement of ER/PR include patient prognosis and patient response to adjuvant endocrine therapy. Individuals with receptor-positive tumors generally have a better prognosis, as indicated by a longer interval to disease recurrence and a longer overall survival, than patients with receptor-negative tumors. Studies have also shown that the determination of receptor status by immunohistochemistry may be useful in predicting patient response to hormonal therapy. Source: LOINC partner 1

Basic Part Properties

Part Display Name
Estrogen+Progesterone receptor
Part Type
Component (Describes the core component or analyte measured)
Created On
2002-06-17
Construct for LOINC Short Name
ERA+PGRA

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP28852-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 雌激素+孕酮受体
Synonyms: ERA+PGRA;雌激素+黄体酮受体
fr-CA French (Canada) Oestrogène+Récepteur progestérone
et-EE Estonian (Estonia) Östrogeeni + progesterooni retseptor
es-ES Spanish (Spain) Receptor de Estrógeno+Progesterona
it-IT Italian (Italy) Estrogeno+Progesterone, recettore
Synonyms: Recettore estrogeno+progesterone
tr-TR Turkish (Turkey) Östrojen+Progesteron reseptörü
ru-RU Russian (Russian Federation) Эстроген+Прогестерон рецептор
nl-NL Dutch (Netherlands) oestrogeen + progesteronreceptor
fr-BE French (Belgium) Récepteur Œstrogènes+ progestérone
Synonyms: Récepteurs stéroides