LP30740-2
MSH2 gene+MLH1 gene
Active
Description
Mutations in the MLH1, MSH2, MSH6, and PMS2 genes, which are involved in DNA mismatch repair, are associated with hereditary nonpolyposis colorectal cancer (HNPCC), an autosomal dominant cancer syndrome that confers an elevated risk of early-onset colorectal cancer (CRC). Patients with HNPCC also have an increased lifetime risk for other cancers of the endometrium, stomach, small intestine, hepatobiliary system, kidney, ureter, and ovary. HNPCC is most often associated with mutations in the MLH1 and MSH2 genes. PMID: 19360696 Source: Regenstrief LOINC, PMID:19360696
Basic Part Properties
- Part Display Name
- MSH2 gene+MLH1 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2002-10-02
- Construct for LOINC Short Name
- MSH2+MLH1 gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP30740-2
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | MSH2 基因+MLH1 基因 Synonyms: 错配修复蛋白-2; |
| et-EE | Estonian (Estonia) | MSH2 geen + MLH1 geen |
| es-ES | Spanish (Spain) | Gen MSH2 + Gen MLH1 |
| it-IT | Italian (Italy) | MSH2, gene+gene MSH1 Synonyms: Gene MSH2+gene MSH1 |
| tr-TR | Turkish (Turkey) | MSH2 geni+MLH1 geni |
| ru-RU | Russian (Russian Federation) | MSH2 ген+MLH1 ген |
| nl-NL | Dutch (Netherlands) | MSH2-gen + MLH1-gen Synonyms: MSH2 gen+MLH1 gen |
LOINC Copyright
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