Version 2.77

Description

Rh is the most complex of the blood groups systems, embracing over 45 distinct antigens, the absence or presence of which combine to exhibit an individual's Rh blood group type. The most clinical important antigen, D or Rho, was the first discovered in 1940 and has been generally referred to as the Rh antigen, being present in over 85% of the random population. Those individuals that lack the D antigen are considered to be Rh negative. The Rh antigens are encoded by two highly homologous and closely linked genes on the short arm of chromosome 1. The RHD gene producing the D antigen, or most of its components; RhCE gene producing the Cc and Ee antigens or their variants. The majority of the antigens within this system represent products of gene cross-over, point mutations or deletions within one or both genes. The Rh antigens appear to be red cell specific, appearing early during development of red blood cells, and have not been found on other body tissues. Antibodies against the Rh antigens have caused severe and fatal transfusion reactions and hemolytic disease of the newborn. The importance of the Rh antigens in the erythroid membrane is exemplified by the fact that in many examples of auto-immune hemolytic anemia, auto-Rh antibodies are frequently found. Source: Serum, Cells and Rare Fluid Exchange, Rh group

Basic Part Properties

Part Display Name
C Ag inferred phenotype
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-03-18
Construct for LOINC Short Name
C Ag inferred

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP310286-2

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) C 抗原推导表型
Synonyms: C 抗原抗原（Ag）推导表型（推导表现型、推导型表现型、推导型表型、推断表型、推演表型）
it-IT Italian (Italy) C Ag fenotipo inferito
es-ES Spanish (Spain) Fenotipo inferido del Ag C