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Description

The SPINK1 gene (serine peptidase inhibitor, Kazal type 1) [HGNC Gene ID:11244] is located on chromosome 5q32. The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008] [NCBI Gene ID:6690] Source: National Center for Biotechnology Information (NCBI) Gene

Reference Information

TypeSourceReference
WebcontentOnline Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. Link to OMIM

Basic Part Properties

Part Name
SPINK1 gene
Part Display Name
SPINK1 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2003-08-08
Construct for LOINC Short Name
SPINK1 gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP31889-6
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Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)SPINK1 基因
Synonyms: Kazal 1 型蛋白酶抑制剂;Kazal 型蛋白酶抑制剂 1;PSTI;TATI;丝氨酸蛋白酶抑制剂, Kazal 型 1;肿瘤相关胰蛋白酶抑制剂;胰分泌性胰蛋白酶抑制剂前体;胰分泌性胰蛋白酶抑制物前体;胰腺分泌型胰蛋白酶抑制剂前体;胰腺分泌型胰蛋白酶抑制因子前体
et-EEEstonian (Estonia)SPINK1 geen
es-ESSpanish (Spain)Gen SPINK1
it-ITItalian (Italy)SPINK1, gene
Synonyms: Gene SPINK1
tr-TRTurkish (Turkey)SPINK1 geni
ru-RURussian (Russian Federation)SPINK1 ген
nl-NLDutch (Netherlands)SPINK1-gen
Synonyms: SPINK1 gen
fr-FRFrench (France)SPINK1 gène
pl-PLPolish (Poland)SPINK1 gen
Synonyms: Gen SPINK1
el-GRGreek (Greece)Γονίδιο SPINK1
Synonyms: Γονίδιο SPINK1