LP32721-0
Vascular endothelial growth factor
Active
Description
Vascular endothelial growth factor (VEGF) is a sub-family of growth factors, specifically the platelet-derived growth factor family of cystine-knot growth factors. The most important member is VEGF-A. Other members are Placenta growth factor (PGF), VEGF-B, VEGF-C and VEGF-D. The latter ones were discovered later than VEGF-A, and, before their discovery, VEGF-A was called just VEGF.
VEGF growth factors are important signaling proteins involved in both vasculogenesis and angiogenesis. When these growth factors are overexpressed, they can contribute to conditions such as cancer, bronchial asthma and diabetes mellitus. Overexpression of VEGFs can also cause vascular disease in the retina of the eye and other parts of the body. Drugs such as bevacizumab can inhibit VEGFs and control or slow those diseases.
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Source: Wikipedia
, Vascular endothelial growth factor (VEGF)
Basic Part Properties
- Part Name
- Vascular endothelial growth factor
- Part Display Name
- Vascular endothelial growth factor
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2003-10-28
- Construct for LOINC Short Name
- VEGF
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Factor de crecimiento endotelial vascular |
| it-IT | Italian (Italy) | Fattore di crescita vascolare endoteliale Synonyms: Fattore di crescita dell''endotelio vascolare |
| tr-TR | Turkish (Turkey) | Vasküler endotel büyüme faktörü |
| ru-RU | Russian (Russian Federation) | Сосудистый эндотелиальный ростовой фактор Synonyms: Фактор роста эндотелия сосудов |
| fr-BE | French (Belgium) | Vascular endothelial growth factor |
| nl-NL | Dutch (Netherlands) | vasculaire endotheliale groeifactor |
| zh-CN | Chinese (China) | 血管内皮细胞生长因子 Synonyms: VEGF; |
| el-GR | Greek (Greece) | Αγγειακός ενδοθηλιακός αυξητικός παράγοντας Synonyms: Αγγειακός ενδοθηλιακός αυξητικός παράγοντας |
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