Version 2.78

Description

The MEN1 gene (multiple endocrine neoplasia I) [HGNC Gene ID:7010] is located on chromosome 11q13. This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008] [NCBI Gene ID:4221] Source: National Center for Biotechnology Information (NCBI) Gene

Reference Information

Type Source Reference
Webcontent Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. Link to OMIM

Basic Part Properties

Part Display Name
MEN1 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2004-02-10
Construct for LOINC Short Name
MEN1 gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP33138-6
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP33138-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) ME1 基因
Synonyms: MEAI;Menin;Menin（一种肿瘤抑制蛋白质, 或者说抑癌蛋白）;Overlapping syndrome;SCG2;Wermer 综合征;Zollinger-Ellison 综合征;卓-艾综合征;卓-艾综合征（主要表现为顽固性消化性溃疡及慢性腹泻）;多内分泌瘤病 1 型;多发性内分泌肿瘤 I 型;多发性内分泌肿瘤 I 型肿瘤抑制蛋白 Menin;多发性内分泌肿瘤Ⅰ型肿瘤抑制蛋白 Menin;多发性内分泌肿瘤形成 I 型;多发性内分泌腺瘤 I 型;多发性内分泌腺瘤Ⅰ型;重叠综合征
et-EE Estonian (Estonia) MEN1 geen
es-ES Spanish (Spain) Gen Men 1
it-IT Italian (Italy) MEN1, gene
Synonyms: Gene MEN1
tr-TR Turkish (Turkey) MEN1 geni
ru-RU Russian (Russian Federation) MEN1 ген
nl-NL Dutch (Netherlands) MEN1-gen
Synonyms: MEN1 gen