Version 2.78

Description

The RPS6KA3 gene (ribosomal protein S6 kinase, 90kDa, polypeptide 3) [HGNC Gene ID:10432] is located on chromosome Xp22.2-p22.1. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008] [NCBI Gene ID:6197] Source: National Center for Biotechnology Information (NCBI) Gene

Reference Information

Type Source Reference
Webcontent Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. Link to OMIM

Basic Part Properties

Part Display Name
RPS6KA3 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2004-02-10
Construct for LOINC Short Name
RPS6KA3 gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP33140-2
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP33140-2

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) RPS6KA3 基因
Synonyms: HU-2;HU-3;ISPK1;ISPK-1;MAPKAPK1B;MRX19;RSK;RSK2;核糖体蛋白 S6 激酶, 90kD, 多肽 3;核蛋白体蛋白 S6 激酶, 90kD, 多肽 3
et-EE Estonian (Estonia) RPS6KA3 geen
es-ES Spanish (Spain) Gen RPS6KA3
it-IT Italian (Italy) RPS6KA3, gene
Synonyms: Gene RPS6KA3
tr-TR Turkish (Turkey) RPS6KA3 geni
ru-RU Russian (Russian Federation) RPS6KA3 ген
nl-NL Dutch (Netherlands) RPS6KA3-gen
Synonyms: RPS6KA3 gen