LP344997-4
F13A1 gene & F13B gene
Active
Description
The F13A1 and F13B genes encode for the 2 subunits of coagulation factor 13, FXIII-A and FXIII-B, which form a heterotetramer zymogen that is activated by thrombin. Mutations in either gene can result in a bleeding disorder known as factor XIII deficiency, with more severe cases (umbilican cord bleeding at birth, CNS hemorrhage, etc.) due to mutations in both copies of the F13A1 gene, with mutations in the F13B gene and/or heterozygous genotypes resulting in more mild disease. PMID: 24401950. Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- F13A1 gene & F13B gene
- Part Display Name
- F13A1 and F13B gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2019-05-14
- Construct for LOINC Short Name
- F13A1 + F13B
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | F13A1 基因 & F13B 基因 |
| it-IT | Italian (Italy) | F13A1, gene & F13B, gene Synonyms: Geni F13A1 e F13B |
| fr-FR | French (France) | F13A1 gène et F13B gène |
| nl-NL | Dutch (Netherlands) | F13A1-gen & F13B-gen |
| es-ES | Spanish (Spain) | Genes F13A1 y F13B |
| pl-PL | Polish (Poland) | F13A1 gen & F13B gen Synonyms: Gen F13A1 i F13B |
| el-GR | Greek (Greece) | Γονίδιο F13A1 & γονίδιο F13B Synonyms: Γονίδιο F13A1 & γονίδιο F13B |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://