LP35626-8

SOD1 gene

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Description

The SOD1 gene (superoxide dismutase 1, soluble) [HGNC Gene ID:11179] is located on chromosome 21q22.11. The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:6647] Source: National Center for Biotechnology Information (NCBI) Gene

Reference Information

Type	Source	Reference
Webcontent	Online Mendelian Inheritance in Man^®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.	Link to OMIM

Basic Part Properties

Part Name: SOD1 gene
Part Display Name: SOD1 gene
Part Type: Component (Describes the core component or analyte measured)
Created On: 2005-04-28
Construct for LOINC Short Name: SOD1 gene

Related Codes

Code System	Code	Code Text	Code Version
HUGO Gene Nomenclature Committee (HGNC)	HGNC:11179	SOD1
National Center for Biotech Info (NCBI) Gene (National Center for Biotechnology Information (NCBI) Gene)	6647	SOD1

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Language Variants Get Info

Tag	Language	Translation
zh-CN	Chinese (China)	SOD1 基因 Synonyms: ALS;ALS1;IPOA;Lou Gehrig 氏病;Lou Gehrig 病;SOD;SOD1基因;吲哚酚氧化酶 A 基因;家族性肌萎缩侧索硬化症 1;肌萎缩侧索硬化症 1;肌萎缩性侧索硬化 1;肌萎缩性脊髓侧索硬化 1;肌萎缩性脊髓侧索硬化症 1;葛雷克症;超氧化物歧化酶 1 基因;铜/锌超氧化物歧化酶基因;铜锌超氧化物歧化酶基因;靛基酚氧化酶 A 基因;靛酚氧化酶 A 基因
et-EE	Estonian (Estonia)	SOD1 geen
es-ES	Spanish (Spain)	Gen SOD1
it-IT	Italian (Italy)	SOD1, gene Synonyms: Gene SOD1
tr-TR	Turkish (Turkey)	SOD1 geni
ru-RU	Russian (Russian Federation)	SOD1 ген
nl-NL	Dutch (Netherlands)	SOD1-gen Synonyms: SOD1 gen
fr-FR	French (France)	SOD1 gène
pl-PL	Polish (Poland)	SOD1 gen Synonyms: Gen SOD1
el-GR	Greek (Greece)	Γονίδιο SOD1 Synonyms: Γονίδιο SOD1

LOINC Copyright

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