LP35690-4
MUTYH gene
Active
Description
The MUTYH gene (mutY homolog) [HGNC Gene ID:7527] is located on chromosome 1p34.1. This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4595] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Name
- MUTYH gene
- Part Display Name
- MUTYH gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2005-05-06
- Construct for LOINC Short Name
- MUTYH gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | MUTYH 基因 Synonyms: mutY (E. coli) 同源基因; |
| et-EE | Estonian (Estonia) | MUTYH geen |
| es-ES | Spanish (Spain) | Gen MUTYH |
| it-IT | Italian (Italy) | MUTYH, gene Synonyms: Gene MUTYH |
| tr-TR | Turkish (Turkey) | MUTYH geni |
| ru-RU | Russian (Russian Federation) | MUTYH ген |
| nl-NL | Dutch (Netherlands) | MUTYH-gen Synonyms: MUTYH gen |
| fr-FR | French (France) | MUTYH gène |
| pl-PL | Polish (Poland) | MUTYH gen Synonyms: Gen MUTYH |
| el-GR | Greek (Greece) | Γονίδιο MUTYH Synonyms: Γονίδιο MUTYH |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://