LP35838-9
TCR alpha beta
Active
Descriptions
Found in most mature, circulating T-cells
Associated with most T-cell neoplasms that express CD3
Source: Regenstrief Institute
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is, in general, responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules.
The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) chain (TCRA gene) and beta (β) chain (TCRB gene), whereas in 5% of T cells this consists of gamma (γ) chain (TCRG gene) and delta (δ) chain (TCRD gene).
When the TCR engages with antigen and MHC, this activates the T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors, specialized accessory molecules and activated or released transcription factors.
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Source: Wikipedia,
wikipedia
Basic Part Properties
- Part Name
- TCR alpha beta
- Part Display Name
- TCR alpha beta
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2005-07-06
- Construct for LOINC Short Name
- TCR A-B
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | TcR alpha beta Synonyms: T 细胞受体 A-B; |
| fr-CA | French (Canada) | Récepteur des cellules T alpha bêta |
| es-ES | Spanish (Spain) | TCR alfa beta |
| it-IT | Italian (Italy) | TCR alfa beta |
| tr-TR | Turkish (Turkey) | TCR alfa beta |
| ru-RU | Russian (Russian Federation) | T клеточный рецептор альфа бета |
| nl-NL | Dutch (Netherlands) | TCR alfa bèta |
| fr-BE | French (Belgium) | Récepteur des cellules T alpha béta |
| fr-FR | French (France) | TCR alpha bêta |
| pl-PL | Polish (Poland) | TCR alfa beta Synonyms: Receptor komórek T alfa beta |
| el-GR | Greek (Greece) | TCR α β Synonyms: TCR α β |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://