Descriptions

Found on some thymocytes and a few mature circulating T-cells
Associated with rare mature T-cell neoplasms and some lymphoblastic lymphomas Source: Regenstrief Institute

The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is, in general, responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules.

The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) chain (TCRA gene) and beta (β) chain (TCRB gene), whereas in 5% of T cells this consists of gamma (γ) chain (TCRG gene) and delta (δ) chain (TCRD gene).

When the TCR engages with antigen and MHC, this activates the T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors, specialized accessory molecules and activated or released transcription factors. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, wikipedia

Basic Part Properties

Part Name
TCR gamma delta
Part Display Name
TCR gamma delta
Part Type
Component (Describes the core component or analyte measured)
Created On
2005-07-06
Construct for LOINC Short Name
TCR G-D

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP35839-7

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)TcR Gamma Delta
Synonyms: TcR G-D;TcR γ-δ;T细胞受体 Gamma Delta;T细胞受体 G-D;T细胞受体 γ-δ
fr-CAFrench (Canada)Récepteur des cellules T gamma delta
es-ESSpanish (Spain)TCR gamma delta
it-ITItalian (Italy)TCR gamma delta
tr-TRTurkish (Turkey)TCR gamma delta
ru-RURussian (Russian Federation)T клеточный рецептор гамма дельта
nl-NLDutch (Netherlands)TCR gamma delta
fr-BEFrench (Belgium)Récepteur des cellules T gamma delta
fr-FRFrench (France)TCR gamma delta
pl-PLPolish (Poland)TCR gamma delta
Synonyms: Receptor limfocyta T gamma delta
el-GRGreek (Greece)TCR γ δ
Synonyms: TCR γ δ