LP35891-8
PDCD10 gene
Active
Description
The PDCD10 gene (programmed cell death 10) [HGNC Gene ID:8761] is located on chromosome 3q26.1. This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] [NCBI Gene ID:11235] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Name
- PDCD10 gene
- Part Display Name
- PDCD10 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2005-07-14
- Construct for LOINC Short Name
- PDCD10 gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP35891-8 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP35891-8
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | PDCD10 基因 Synonyms: CCM3; |
| es-ES | Spanish (Spain) | Gen PDCD10 |
| it-IT | Italian (Italy) | PDCD10, gene Synonyms: Gene PDCD10 |
| et-EE | Estonian (Estonia) | PDCD10 geen |
| tr-TR | Turkish (Turkey) | PDCD10 geni |
| ru-RU | Russian (Russian Federation) | PDCD10 ген |
| nl-NL | Dutch (Netherlands) | PDCD10-gen Synonyms: PDCD10 gen |
| el-GR | Greek (Greece) | Γονίδιο PDCD10 Synonyms: Γονίδιο PDCD10 |
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://