LP36006-2
Fc epsilon RI
Active
Descriptions
Present on the surface of resting mast cells, basophils, Langerhans cells and other cell types. Source: Regenstrief Institute
The high-affinity IgE receptor, also known as FcεRI, or Fc epsilon RI, is the high-affinity receptor for the Fc region of immunoglobulin E (IgE), an antibody isotype involved in the allergy disorder and parasites immunity. FcεRI is a tetrameric receptor complex consisting of one alpha (FcεRIα - antibody binding site), one beta (FcεRIβ - which amplifies the downstream signal), and two disulfide bridge connected gamma chains (FcεRIγ - the site where the downstream signal initiates). It is constitutively expressed on mast cells and basophils and is inducible in eosinophils.
FcεRI is found on epidermal Langerhans cells, eosinophils, mast cells, and basophils. As a result of its cellular distribution, this receptor plays a major role in controlling allergic responses. FcεRI is also expressed on antigen-presenting cells, and controls the production of important immune mediators (cytokines, interleukins, leukotrienes, and prostaglandins) that promote inflammation. The most famous mediator is histamine, which results in the five symptoms of inflammation: heat, swelling, pain, redness and itchiness.
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Source: Wikipedia
, Wikipedia
Basic Part Properties
- Part Name
- Fc epsilon RI
- Part Display Name
- Fc epsilon RI
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2005-08-08
- Construct for LOINC Short Name
- Fc epsilon RI
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | Fc Epsilon 受体 I 型 Synonyms: 高亲合力 IgE 受体; |
| es-ES | Spanish (Spain) | Fc Epsion RI |
| it-IT | Italian (Italy) | Fc epsilon RI |
| tr-TR | Turkish (Turkey) | Fc epsilon RI |
| ru-RU | Russian (Russian Federation) | Fc эпсилон RI |
| fr-BE | French (Belgium) | Fc epsilon RI |
| fr-CA | French (Canada) | Fc epsilon RI |
| nl-NL | Dutch (Netherlands) | Fc epsilon RI |
| el-GR | Greek (Greece) | FcεRI Synonyms: FcεRI |
LOINC Copyright
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