LP36432-0
Hepatitis B virus YMDD mutation
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Description
In hepatitis B, lamivudine resistance was first described in the YMDD locus of the HBV reverse transcriptase gene. The HBV reverse transcriptase gene is 344 amino acids long and occupies codons 349 to 692 on the viral genome. The most commonly encountered resistance mutations are M204V/I/S. The change in amino acid sequence from YMDD to YIDD results in a 3.2 fold reduction in the error rate of the reverse transcriptase, which correlates with a significant growth disadvantage of the virus. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia
Basic Part Properties
- Part Name
- Hepatitis B virus YMDD mutation
- Part Display Name
- Hepatitis B Virus YMDD
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2005-12-19
- Construct for LOINC Short Name
- HBV YMDD Mut
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 乙型肝炎病毒 YMDD 突变 Synonyms: HBV YMDD Mut; |
| es-ES | Spanish (Spain) | Gen GDAP1 |
| it-IT | Italian (Italy) | Epatite B virus, mutazione YMDD Synonyms: Mutazione YMDD del virus dell''epatite B |
| et-EE | Estonian (Estonia) | B-hepatiidi viiruse YMDD mutatsioon |
| tr-TR | Turkish (Turkey) | Hepatit B virüsü YMDD mutasyonu |
| ru-RU | Russian (Russian Federation) | Гепатит B вирус YMDD мутация |
| fr-BE | French (Belgium) | Mutants YMDD du virus de l'hépatite B |
| fr-CA | French (Canada) | Mutants YMDD du virus de l'hépatite B |
| nl-NL | Dutch (Netherlands) | Hepatitis B-virus YMDD mutatie |
| pl-PL | Polish (Poland) | Wirus zapalenia wątroby typu B, mutacja YMDD |
| el-GR | Greek (Greece) | Μετάλλαξη YMDD του ιού της ηπατίτιδας Β Synonyms: Μετάλλαξη YMDD του ιού της ηπατίτιδας Β |
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