LP36885-9
DPYD gene
Active
Description
The DPYD gene (dihydropyrimidine dehydrogenase) [HGNC Gene ID:3012] is located on chromosome 1 at position p22. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] [NCBI Gene ID:1806] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Name
- DPYD gene
- Part Display Name
- DPYD gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2006-04-28
- Construct for LOINC Short Name
- DPYD gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | DPYD 基因 Synonyms: DHP; |
| et-EE | Estonian (Estonia) | DPYD geen |
| es-ES | Spanish (Spain) | Gen DPYD |
| it-IT | Italian (Italy) | DPYD, gene Synonyms: Gene DPYD |
| tr-TR | Turkish (Turkey) | DPYD geni |
| ru-RU | Russian (Russian Federation) | DPYD ген |
| nl-NL | Dutch (Netherlands) | DPYD-gen Synonyms: DPYD gen |
| fr-FR | French (France) | DPYD gène |
| pl-PL | Polish (Poland) | DPYD gen Synonyms: Gen DPYD |
| el-GR | Greek (Greece) | Γονίδιο DPYD Synonyms: Γονίδιο DPYD |
LOINC Copyright
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