LP40500-8
CYP2C9 gene
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Description
The CYP2C9 gene (cytochrome P450, family 2, subfamily C, polypeptide 9) [HGNC Gene ID:2623] is located on chromosome 10q24. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008] [NCBI Gene ID:1559] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Name
- CYP2C9 gene
- Part Display Name
- CYP2C9 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2006-08-25
- Construct for LOINC Short Name
- CYP2C9 gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CYP2C9 基因 Synonyms: CPC9; |
| es-ES | Spanish (Spain) | Gen CYP2C9 |
| it-IT | Italian (Italy) | CYP2C9, gene Synonyms: Gene CYP2C9 |
| et-EE | Estonian (Estonia) | CYP2C9 geen |
| tr-TR | Turkish (Turkey) | CYP2C9 geni |
| ru-RU | Russian (Russian Federation) | CYP2C9 ген |
| nl-NL | Dutch (Netherlands) | CYP2C9-gen Synonyms: CYP2C9 gen |
| el-GR | Greek (Greece) | Γονίδιο CYP2C9 Synonyms: Γονίδιο CYP2C9 |
LOINC Copyright
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