Version 2.80

Description

The ITGA2B gene (integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)) [HGNC Gene ID:6138] is located on chromosome 17q21.32. ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3674] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
Platelet CD41
Part Display Name
Platelet CD41
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-06-28
Construct for LOINC Short Name
Plt CD41

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP410814-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 血小板 CD41
it-IT Italian (Italy) Piastrine CD41
es-ES Spanish (Spain) CD41 plaquetario
pl-PL Polish (Poland) Płytkowy antygen CD41
el-GR Greek (Greece) Αιμοπετάλιο CD41
Synonyms: Αιμοπετάλιο CD41