Version 2.77

Description

The Ambler classification for carbapenemases utilizes four molecular classes - A, B, C and D. The OXA group of β-lactamases occur mainly in Acinetobacter species and are part of molecular class D. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. PMID: 24696435. Many OXA enzymes (OXA-23-like, OXA-24-like, OXA-48-like, OXA-58-like) are considered to be responsible for the worldwide resistance epidemics. OXA-23-like enzymes have been isolated in carbapenem-resistant Acinetobacter baumannii (CR-AB) in both the US and in China, revealing the importance of national and global efforts to control the spread of CR-AB.
PMID: 24629777 PMID: 26617588 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Bacterial carbapenem resistance blaOXA-24-like+blaOXA-48-like genes
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-08-28
Construct for LOINC Short Name
blaOXA-24+48-like

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP411469-2

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 细菌碳青霉烯类耐药 blaOXA-23-样基因+blaOXA-48-样基因
Synonyms: 细菌细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaOXA-134-样基因+blaOXA-48-样基因
it-IT Italian (Italy) Resistenza batterica ai carbapenemici, geni blaOXA-23-like+blaOXA-48-like
Synonyms: Geni blaOXA-24-like+blaOXA-48-like di resistenza batterica ai carbapenemi
nl-NL Dutch (Netherlands) bacteriële carbapenemresistentie blaOXA-23-achtig + blaOXA-48-achtig genen
Synonyms: blaOXA-134-like
es-ES Spanish (Spain) Genes de resistencia a los carbapenémicos bacterianos similares a blaOXA-23 + similares a blaOXA-48