LP417252-6
24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol
Active
Description
24,25-dihydroxyvitamin D (24,25 DHD), also known as 24r-Hydroxycalcidiol, is an INactive metabolite produced by alternative hydroxylation of 25 hydroxyvitamin D (25HDN) by the CYP24A1 enzyme. The hydroxylation by CYP24A1 competes with hydroxylation to active form 1,25-dihydroxyvitamin D (1,25 DHD) by the CYP27B1 enzyme, and is an important process that prevents overproduction of 1,25 DHD and resulting vitamin D toxicity. Testing for an elevated ratio of 25HDN to 24,25 DHD can be used to reveal the likely presence of mutations in the CYP24A1 gene PMID: 22648296. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- 24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2019-12-20
- Construct for LOINC Short Name
- 24,25(OH)2 VitD
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP417252-6
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 24r-羟基钙二醇+24r,25-羟基钙化醇 |
| nl-NL | Dutch (Netherlands) | 24,25-dihydroxyvitamine D3 + 24,25-dihydroxyvitamine D2 Synonyms: vitamine D3 + D2 |
| it-IT | Italian (Italy) | 24r-Idrossicalcidiolo+24r-Idrossicalcidiolo Synonyms: 24,25-Diidrossivitamina D3+24,25-diidrossivitamina D2 |
| es-ES | Spanish (Spain) | 24,25-dihidroxivitamina D3 + 24,25-dihidroxivitamina D2 |
LOINC Copyright
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