Version 2.77

Description

LAD-1 is clinically characterized by recurrent infections, impaired wound healing, delayed umbilical cord separation, persistent leukocytosis, and recurrent soft tissue and oral infections. Each of the beta2-integrins is a heterodimer composed of an alpha chain (CD11a, CD11b, or CD11c) noncovalently linked to a common beta2-subunit (CD18). The alpha-beta heterodimers of the beta2-integrin family include LFA-1 (CD11a/CD18), Mac-1/CR3 (CD11b/CD18), and p150/95 (CD11c/CD18).(1-4) The CD18 gene, ITGB2, and its product are required for normal expression of the alpha-beta heterodimers. Therefore, defects in CD18 expression lead to either very low or no surface membrane expression of CD11a, CD11b, and CD11c. Copyright Copyright © 1995-2009 Source: Mayo Medical Laboratories

Basic Part Properties

Part Display Name
CD11a, CD11b, and CD18 phenotyping panel
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-12-31
Construct for LOINC Short Name
CD11a + CD11b + CD18 Pnl

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP417291-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) CD11a 与 CD11b 与 CD18 表现型分型组套
Synonyms: CD11a 与 CD11b 与 CD18 表现型分型(表型分型、表现型分析、表型分析)组套(组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目)
nl-NL Dutch (Netherlands) CD11a & CD11b & CD18 fenotypering panel
it-IT Italian (Italy) CD11a & CD11b & CD18, panel fenotipizzazione
Synonyms: Panel fenotipizzazione CD11a, CD11b, e CD18
es-ES Spanish (Spain) Panel de fenotipado de CD11a, CD11b y CD18
pl-PL Polish (Poland) CD11a & CD11b & CD18, panel fenotypujący
Synonyms: CD11a & CD11b & CD18, panel fenotypujący