LP417291-4
CD11a & CD11b & CD18 phenotyping panel
Active
Description
LAD-1 is clinically characterized by recurrent infections, impaired wound healing, delayed umbilical cord separation, persistent leukocytosis, and recurrent soft tissue and oral infections. Each of the beta2-integrins is a heterodimer composed of an alpha chain (CD11a, CD11b, or CD11c) noncovalently linked to a common beta2-subunit (CD18). The alpha-beta heterodimers of the beta2-integrin family include LFA-1 (CD11a/CD18), Mac-1/CR3 (CD11b/CD18), and p150/95 (CD11c/CD18).(1-4) The CD18 gene, ITGB2, and its product are required for normal expression of the alpha-beta heterodimers. Therefore, defects in CD18 expression lead to either very low or no surface membrane expression of CD11a, CD11b, and CD11c. Copyright Copyright © 1995-2009 Source: Mayo Medical Laboratories
Basic Part Properties
- Part Display Name
- CD11a, CD11b, and CD18 phenotyping panel
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2019-12-31
- Construct for LOINC Short Name
- CD11a + CD11b + CD18 Pnl
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP417291-4
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | CD11a 与 CD11b 与 CD18 表现型分型组套 Synonyms: CD11a 与 CD11b 与 CD18 表现型分型(表型分型、 |
nl-NL | Dutch (Netherlands) | CD11a & CD11b & CD18 fenotypering panel |
it-IT | Italian (Italy) | CD11a & CD11b & CD18, panel fenotipizzazione Synonyms: Panel fenotipizzazione CD11a, CD11b, e CD18 |
es-ES | Spanish (Spain) | Panel de fenotipado de CD11a, CD11b y CD18 |
pl-PL | Polish (Poland) | CD11a & CD11b & CD18, panel fenotypujący Synonyms: CD11a & CD11b & CD18, panel fenotypujący |
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