Description

The FGA gene (fibrinogen alpha chain) [HGNC Gene ID:3661] is located on chromosome 4q31.3. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016] [NCBI Gene ID:2243] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
FGA gene
Part Display Name
FGA gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-01-13
Construct for LOINC Short Name
FGA

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP417392-0
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Language Variants Get Info

TagLanguageTranslation
nl-NLDutch (Netherlands)FGA-gen
zh-CNChinese (China)FGA 基因
Synonyms: 纤维蛋白原α链基因;纤维蛋白原 Alpha 链基因;Fibrinogen Alpha Chain gene
fr-FRFrench (France)FGA gène
it-ITItalian (Italy)FGA, gene
es-ESSpanish (Spain)Gen FGA
pl-PLPolish (Poland)FGA gen
Synonyms: Gen FGA
el-GRGreek (Greece)Γονίδιο FGA
Synonyms: Γονίδιο FGA