Description

The MMADHC gene (metabolism of cobalamin associated D) [HGNC Gene ID:25221] is located on chromosome 2q23.2. This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.[provided by RefSeq, Nov 2008] [NCBI Gene ID:27249] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
MMADHC gene
Part Display Name
MMADHC gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-01-13
Construct for LOINC Short Name
MMADHC

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP417408-4
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP417408-4

Language Variants Get Info

TagLanguageTranslation
nl-NLDutch (Netherlands)MMADHC-gen MMADHC-gen
zh-CNChinese (China)MMADHC 基因
Synonyms: Metabolism Of Cobalamin Associated D gene;高同型半胱氨酸血症D型基因;钴胺素代谢相关缺陷D型基因
fr-FRFrench (France)MMADHC gène
it-ITItalian (Italy)MMADHC, gene
es-ESSpanish (Spain)Gen MMADHC
pl-PLPolish (Poland)MMADHC gen
Synonyms: Gen MMADHC
el-GRGreek (Greece)Γονίδιο MMADHC
Synonyms: Γονίδιο MMADHC