LP417565-1
CYP1A2 gene allele
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Description
Genetic screening for abnormal CYP1A2 metabolism is focused on the presence of *1C (-3860G>A), *1F (163C>A) and *1K (-729C>T) genetic polymorphisms. Individuals homozygous for *1F have higher CYP1A2 activity in the presence of CYP1A2 inducers. The *1C and *1K alleles are associated with decreased CYP1A2 activity with intermediate metabolism when 1 allele is present and slow (poor) metabolism when 2 alleles are present. Inducers for CYP1A2 activity include smoking, coffee, omeprazole, insulin. Inhibitors include oral contraceptives. The genotype results may be used to determine a patient's drug dose adjustment. Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- CYP1A2 gene allele
- Part Display Name
- CYP1A2 gene allele
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2020-01-30
- Construct for LOINC Short Name
- CYP1A2 allele
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP417565-1 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP417565-1
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CYP1A2 基因等位基因 |
| nl-NL | Dutch (Netherlands) | CYP1A2-allel |
| it-IT | Italian (Italy) | CYP1A2, gene allele |
| es-ES | Spanish (Spain) | Alelo del gen CYP1A2 |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://