LP417567-7
CYP2C19 gene allele
Active
Description
Cytochrome P450-2C19 (CYP2C19; [HGNC Gene ID: 2621]), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism 10-15% of drugs in current clinical use. Genetic variations in CYP2C19 can affect the response (i.e., efficacy or toxicity) to drugs metabolized by CYP2C19 and selection of alternative dosing or agents may be necessary in individuals with specific CYP2C19 genetic variations. PMID: 23486447 PMID: 23698643 PMID: 25974703 See https://www.pharmgkb.org/gene/PA124 for more information and dosing guidelines for drugs impacted by CYP2C19 genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium
Basic Part Properties
- Part Display Name
- CYP2C19 gene allele
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2020-01-30
- Construct for LOINC Short Name
- CYP2C19 allele
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP417567-7 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP417567-7
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CYP2C19 基因等位基因 |
| nl-NL | Dutch (Netherlands) | CYP2C19-allel |
| it-IT | Italian (Italy) | CYP2C19, gene allele |
| es-ES | Spanish (Spain) | Alelo del gen CYP2C19 |
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