LP417569-3
CYP2D6 gene allele
Active
Description
Cytochrome P450-2D6 (CYP2D6;[HGNC Gene ID: 2625]), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism approximately 25% of drugs in current clinical use. Genetic variations in CYP2D6 can affect the response (i.e., efficacy or toxicity) to drugs metabolized by CYP2D6 and selection of alternative dosing or agents may be necessary in individuals with specific CYP2D6 genetic variations. PMID: 23486447 PMID: 24458010 PMID: 25974703. See https://www.pharmgkb.org/gene/PA128 for more information and dosing guidelines for drugs impacted by CYP2D6 genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium
Basic Part Properties
- Part Display Name
- CYP2D6 gene allele
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2020-01-30
- Construct for LOINC Short Name
- CYP2D6 allele
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP417569-3 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP417569-3
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CYP2D6 基因等位基因 |
| nl-NL | Dutch (Netherlands) | CYP2D6-allel |
| it-IT | Italian (Italy) | CYP2D6, gene allele |
| es-ES | Spanish (Spain) | Alelo del gen CYP2D6 |
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