LP417570-1
CYP3A4 gene allele
Active
Description
Cytochrome P450 3A4 (abbreviated CYP3A4) is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Over 30 single nucleotide polymorphisms (SNPs) have been identified in this gene, most of which are not clinically significant. Few have been found to decrease catalytic activity with certain ligands, including testosterone and nifedipine, in comparison to wild-type metabolism. Examples of these alleles and associated SNPs include CYP3A4*6 (an A17776 insertion), CYP3A4*17 (15615T>C) and CYP3A4*22 (15389C>T). A full list of alleles, nucleotide changes and their described enzymatic activity can be found at http://www.cypalleles.ki.se/cyp3a4.htm. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- CYP3A4 gene allele
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2020-01-30
- Construct for LOINC Short Name
- CYP3A4 allele
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP417570-1 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP417570-1
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CYP3A4 基因等位基因 |
| nl-NL | Dutch (Netherlands) | CYP3A4-allel |
| it-IT | Italian (Italy) | CYP3A4, gene allele |
| es-ES | Spanish (Spain) | Alelo del gen CYP3A4 |
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