Version 2.78

Description

Cytochrome P450-3A5 (CYP3A5; [HGNC Gene ID: 2638]), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism many drugs in current clinical use. Genetic variations in CYP3A5 can affect the response (i.e., efficacy or toxicity) to drugs metabolized by CYP3A5 and selection of alternative dosing or agents may be necessary in individuals with specific CYP3A5 genetic variations. PMID: 25801146 See https://www.pharmgkb.org/gene/PA131 for more information and dosing guidelines for drugs impacted by CYP3A5 genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium

Basic Part Properties

Part Display Name
CYP3A5 gene allele
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-01-30
Construct for LOINC Short Name
CYP3A5 allele

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP417571-9
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP417571-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) CYP3A5 基因等位基因
nl-NL Dutch (Netherlands) CYP3A5-allel
it-IT Italian (Italy) CYP3A5, gene allele
es-ES Spanish (Spain) Alelo del gen CYP3A5