LP417746-7
Alpha defensins 1+2+3
Active
Description
Human neutrophil peptides (HNPs), also known as alpha defensins, are antimicrobial peptides released by activated neutrophils in response to infection. HNP-1 and HNP-2 are encoded by the DEFA1 gene, and HNP-3 is encoded by DEFA3 gene. All three peptides are nearly identical; they only differ by the first amino acid in their sequence. HNPs have antibacterial, fungicide and antiviral activities. PMID: 15616305 They have been extensively studied as a biomarker in various diseases such as infections, atherosclerosis, rheumatic diseases, preeclampsia, and cancer. PMID: 16513165 PMID: 19186224 PMID: 25196784 HNP synovial fluid proteins are used as a diagnostic biomarker for periprosthetic joint infection (PJI). PMID: 31856885 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Alpha defensins 1+2+3
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2020-02-18
- Construct for LOINC Short Name
- Alpha defensins 1+2+3
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | Alpha 防御素 1+2+3 Synonyms: α防御素 1+2+3; |
| nl-NL | Dutch (Netherlands) | alfa-defensine 1 + 2 + 3 |
| it-IT | Italian (Italy) | Alfa defensine 1+2+3 |
| es-ES | Spanish (Spain) | Alfa defensinas 1+2+3 |
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