Description

Tocilizumab is a recombinant humanized monoclonal antibody against the interleukin-6 receptor being used to treat patients with COVID-19 pneumonia. Such patients are in danger of developing a hyperimmune response known as a cytokine storm which is characterized by an increased production of cytokines. The cytokines cause damage and lung tissue fibrosis that can last an extensive amount of time. The current treatment for COVID-19 includes the use of anti-viral and immunomodulatory drugs, including tocilizumab. Tocilizumab is also used to treat severe rheumatoid arthritis, systemic juvenile idiopathic arthritis, giant cell arteritis, and life-threatening cytokine release syndrome induced by chimeric antigen receptor T cell therapy.https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(20)30173-9/fulltext Source: Regenstrief LOINC

Basic Part Properties

Part Name
Tocilizumab
Part Display Name
Tocilizumab
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-09-13
Construct for LOINC Short Name
Tocilizumab

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP420287-7

Language Variants Get Info

TagLanguageTranslation
fr-FRFrench (France)Tocilizumab
it-ITItalian (Italy)Tocilizumab
nl-NLDutch (Netherlands)tocilizumab
es-ESSpanish (Spain)Tocilizumab
zh-CNChinese (China)托珠单抗
Synonyms: 免疫球蛋白IgG1(γ1,κ)子类重组人源化抗-人白介素6(IL-6)受体单抗;雅美罗;IL-6受体单抗;Actemra;IL-6受体抑制剂;托珠单抗
el-GRGreek (Greece)Τοσιλιζουμάμπη
Synonyms: Τοσιλιζουμάμπη