LP420454-3
Inner ear 68kD Ab.IgG
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Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Mayo Medical LaboratoriesCopyright Copyright © 1995-2009 | Autoantibodies to 68kD inner ear antigen are associated with autoimmune inner ear disease (AIED) and is currently the best biomarker available to diagnose AIED. Patients with AIED typically experience hearing loss and tinnitus over several months, but variations of the onset of AIED can include bilateral attacks of hearing loss, attacks of dizziness, and the presence of autoantibodies. Hair cells in the inner ear are commonly affected and damage to them leads to hearing loss and problems with balance. The cause of AIED is believed to be due to damage of the inner ear from autoantibodies or immune cells and cytokines due to inflammation. Viral or bacterial infections may induce the production of antibodies that cross react with inner ear antigens.https://www.dizziness-and-balance.com/disorders/autoimmune/aied.html Seventy percent of patients diagnosed with autoimmune hearing loss test positive for antibodies to the 68kD inner ear antigen and the antibody level correlates with the severity of the disease. The majority of patients with 68kD inner ear antigen autoantibodies respond well to corticosteroid treatment. (Hirose et al: The Laryngoscope 109:1769 - 1999) |
Basic Part Properties
- Part Name
- Inner ear 68kD Ab.IgG
- Part Display Name
- Inner ear 68kD Ab.IgG
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2020-10-08
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| fr-FR | French (France) | Oreille interne 68kD anticorps IgG |
| pl-PL | Polish (Poland) | Antygen ucha wewnętrznego 68kD Ab.IgG Synonyms: Przeciwciała IgG do antygenu ucha wewnętrznego 68kD |
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