Reference Information

TypeSourceReference
ArticleRegenstrief LOINCMacrophage inflammatory protein 1 alpha (MIP-1 alpha) is chemotactic cytokine that is a member of the CC subfamily of chemokines. It is secreted by macrophages that are typically increased in areas of inflammation and bone resorption. MIP-1 alpha attracts other macrophages, lymphocytes, and eosinophils by way of the CCR1 and CCR5 receptors present on the surface of macrophages. Also, MIP-1 alpha promotes wound healing, inhibits stem cells, and maintains effector immune responses. MIP-1 alpha plays an influential pathogenic role in diseases that are associated with inflammation and bone resorption including periodontitis, multiple myeloma, Sjogren syndrome, and rheumatoid arthritis. MIP-1 alpha may be used as a biomarker for inflammatory diseases in the future. PMCID: PMC7124056

Basic Part Properties

Part Name
Macrophage inflammatory protein 1.alpha
Part Display Name
Macrophage inflammatory protein 1 alpha
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-11-10
Construct for LOINC Short Name
MIP-1 alpha

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP421050-8

Language Variants Get Info

TagLanguageTranslation
fr-FRFrench (France)MIP-1a
it-ITItalian (Italy)Proteina infiammatoria dei macrofagi 1-alfa,proteina infiammatoria dei macrofagi 1 alfa, MIP-1-alpha
es-ESSpanish (Spain)Proteína inflamatoria de macrófagos 1.alpha
zh-CNChinese (China)巨噬细胞炎性蛋白 1.alpha
Synonyms: 巨噬细胞炎性蛋白 1.α;巨噬细胞炎性蛋白 1-α;巨噬细胞炎性蛋白 1-alpha;巨噬细胞炎症蛋白 1.α;巨噬细胞炎症蛋白 1-α;macrophage inflammatory protein 1-α;MIP-1α;MIP-1 alpha
pl-PLPolish (Poland)Białko zapalne makrofagów 1.alfa
Synonyms: Białko zapalne makrofagów 1 alfa;MIP-1 α;MIP-1 alfa;CCL3
el-GRGreek (Greece)Φλεγμονώδης πρωτεΐνη μακροφάγων 1.α
Synonyms: Φλεγμονώδης πρωτεΐνη μακροφάγων 1.α