LP422606-6
CD79B gene
Active
Description
The CD79A and CD79B genes, located on chromosomes 19 and 17, respectively, encode the alpha and beta chains of the B-cell antigen receptor complex-associated protein. When an antigen binds to the B-cell antigen receptor (BCR) complex, the B-cell antigen receptor complex-associated protein initiates a signal transduction cascade that results in internalization of the BCR complex, transport to late endosomes, and antigen presentation. The beta chain also plays a role in phosphorylation of the alpha chain. Mutations in CD79B are associated with agammaglobulinemia 6, an autosomal recessive disease associated with low or absent serum antibodies and circulating B-cells that is characterized by severe infections early in childhood. [UniProt: P11912] [UniProt: P40259] Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- CD79B gene
- Part Display Name
- CD79B gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2021-02-22
- Construct for LOINC Short Name
- CD79B
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| fr-FR | French (France) | CD79B gène |
| it-IT | Italian (Italy) | CD79B, gene |
| nl-NL | Dutch (Netherlands) | CD79B-gen |
| pl-PL | Polish (Poland) | CD79B gen Synonyms: Gen CD79B |
| es-ES | Spanish (Spain) | Gen CD79B |
| zh-CN | Chinese (China) | CD79B 基因 Synonyms: CD79b Molecule gene; |
| el-GR | Greek (Greece) | Γονίδιο CD79B Synonyms: Γονίδιο CD79B |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://