Version 2.77

Description

Hepatitis A virus cellular receptor (HAVCR) 1 protein, also known by kidney injury molecule 1, KIM-1, TIM-1, and other names, acts as a receptor for multiple viruses, including Hepatitis A, Ebola, Marburg, Dengue, and Zika. It also may play a role in kidney injury and repair, as well as development of T-helper cells. [UniProt: Q96D42] HAVCR-1 is expressed on proximal tubule cells in the kidney and is not detectable in the urine in the absence of disease, making it a specific and sensitive indicator of damage to the proximal tubule. Expression of this protein is associated with tubulointerstitial inflammation, including proteinuric nephropathy. Elevated levels of the protein may be associated with decline in GFR. PMID: 29577044 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Hepatitis A virus cellular receptor 1
Part Type
Component (Describes the core component or analyte measured)
Created On
2021-03-05
Construct for LOINC Short Name
HAVcr-1

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP422762-7

Language Variants Get Info

Tag Language Translation
it-IT Italian (Italy) Epatite A virus, recettore cellulare 1
Synonyms: Recettore cellulare 1 del virus dell''epatite A
es-ES Spanish (Spain) Receptor celular 1 del virus de la hepatitis A
zh-CN Chinese (China) 甲型肝炎病毒细胞受体 1
Synonyms: 甲型肝炎病毒（HAV、甲肝病毒、甲肝）细胞受体 1;HAVCR1
pl-PL Polish (Poland) Wirus zapalenia wątroby typu A receptor komórkowy 1
Synonyms: Receptor komórkowy 1 wirusa zapalenia wątroby typu A