Version 2.78

Description

CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF family of molecules. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In general, CD40L plays the role of a costimulatory molecule and induces activation in APC in association with T cell receptor stimulation by MHC molecules on the APC. The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene, which could result in either reduced expression or normal expression with reduced functional binding to CD40, results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD154

Basic Part Properties

Part Display Name
CD154 expression and function panel
Part Type
Component (Describes the core component or analyte measured)
Created On
2021-07-20
Construct for LOINC Short Name
CD154 Expr+Func Pnl

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP428359-6

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de expresión y función de CD154
nl-NL Dutch (Netherlands) CD154-expressie & -functie panel
it-IT Italian (Italy) CD154 espressione & funzione, panel
Synonyms: Panel CD154 espressione e funzione
zh-CN Chinese (China) CD154 表达与功能组套
Synonyms: CD154 表达与功能组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）
pl-PL Polish (Poland) Panel ekspresji i funkcji CD154
Synonyms: Panel ekspresji i funkcji CD154