LP433457-1
Neurofilament light chain
Active
Description
Neurofilament light chain (NfL) is a neuronal cytoplasmic protein highly expressed in large myelinated axons. Its levels increase in CSF and blood proportionally to the degree of axonal damage in a variety of neurological disorders. The role of NfL as a biomarker has been largely reported in multiple sclerosis (MS), Alzheimer's disease (AD), frontotemporal dementia (FTD), ALS, atypical parkinsonian disorders (APD) and traumatic brain injury (TBI). In one specific use, serum NfL levels are markedly elevated in atypical parkinsonisms compared to Parkinson disease. PMID: 30967444 Source: PubMed Health
Basic Part Properties
- Part Name
- Neurofilament light chain
- Part Display Name
- Neurofilament light chain
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2022-08-09
- Construct for LOINC Short Name
- Nfl chain
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| it-IT | Italian (Italy) | Catena leggera del neurofilamento |
| zh-CN | Chinese (China) | 神经丝蛋白轻链 Synonyms: 神经丝蛋白（神经丝、 |
| nl-NL | Dutch (Netherlands) | lichte keten van neurofilament |
| es-ES | Spanish (Spain) | Cadena ligera de neurofilamento |
| fr-FR | French (France) | Chaine légère de neurofilament |
| el-GR | Greek (Greece) | Νευροϊνίδια ελαφράς αλύσου Synonyms: Νευροϊνίδια ελαφράς αλύσου |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://