LP61808-9
3-Methyladipate
Active
Description
3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation. This pathway produces 3-methyladipic acid as the final metabolite, which is excreted in the urine (Wanders et al. 2001). Activity of the w-oxidation pathway is approximately doubled in ARD patients compared with normal individuals PMID: 11948235. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , Human Metabolome Database
Basic Part Properties
- Part Name
- 3-Methyladipate
- Part Display Name
- 3-Methyladipate
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2006-12-12
- Construct for LOINC Short Name
- 3-Methyladipate
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 3-甲基己二酸 |
| es-ES | Spanish (Spain) | 3-Metil-ladipato |
| it-IT | Italian (Italy) | 3-Metiladipato |
| et-EE | Estonian (Estonia) | 3-metüüladipaat |
| tr-TR | Turkish (Turkey) | 3-Metiladipat |
| ru-RU | Russian (Russian Federation) | 3-Метиладипат |
| fr-BE | French (Belgium) | 3-méthyladipate |
| fr-CA | French (Canada) | 3-méthyladipate |
| nl-NL | Dutch (Netherlands) | 3-methyladipaat |
| el-GR | Greek (Greece) | 3-μεθυλαδιπικό οξύ Synonyms: 3-μεθυλαδιπικό οξύ |
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