Version 2.80

Description

The SERPINE1 gene (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1) [HGNC Gene ID:8583] is located on chromosome 7q22.1. This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] [NCBI Gene ID:5054] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
SERPINE1 gene
Part Display Name
SERPINE1 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2007-01-03
Construct for LOINC Short Name
SERPINE1 gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP62082-0
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP62082-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) SERPINE1 基因
Synonyms: PAI;PAI 1;PAI1;PAI-1;PLANH1;Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;丝氨酸 (或半胱氨酸) 蛋白酶抑制剂, 分化枝
es-ES Spanish (Spain) Gen SERPINE1
it-IT Italian (Italy) SERPINE1, gene
Synonyms: Gene SERPINE1
et-EE Estonian (Estonia) SERPINE1 geen
tr-TR Turkish (Turkey) SERPINE1 geni
ru-RU Russian (Russian Federation) SERPINE1 ген
nl-NL Dutch (Netherlands) SERPINE1-gen
Synonyms: SERPINE1 gen
el-GR Greek (Greece) Γονίδιο SERPINE1
Synonyms: Γονίδιο SERPINE1