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Description

The PROS1 gene (protein S (alpha)) [HGNC Gene ID:9456] is located on chromosome 3q11.2. This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq, Feb 2009] [NCBI Gene ID:5627] Source: National Center for Biotechnology Information (NCBI) Gene

Reference Information

TypeSourceReference
WebcontentOnline Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. Link to OMIM

Basic Part Properties

Part Name
PROS1 gene
Part Display Name
PROS1 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2007-01-12
Construct for LOINC Short Name
PROS1 gene

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Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)PROS1 基因
Synonyms: PROS;protein S (alpha);protein Sa;PS21;PS22;PS23;PS24;PS25;PSA;蛋白 S (alpha);蛋白 S (α);蛋白 Sa;蛋白 Sα
et-EEEstonian (Estonia)PROS1 geen
es-ESSpanish (Spain)Gen PROS1
it-ITItalian (Italy)PROS1, gene
Synonyms: Gene PROS1
tr-TRTurkish (Turkey)PROS1 geni
ru-RURussian (Russian Federation)PROS1 ген
nl-NLDutch (Netherlands)PROS1-gen
Synonyms: PROS1 gen
fr-FRFrench (France)PROS1 gène
pl-PLPolish (Poland)PROS1 gen
Synonyms: Gen PROS1
el-GRGreek (Greece)Γονίδιο PROS1
Synonyms: Γονίδιο PROS1