LP63483-9
MDCR gene
Active
Description
The MDCR gene (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon) gene is located on chromosome 17p13.3. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008] [NCBI Gene ID:7531] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Name
- MDCR gene
- Part Display Name
- MDCR gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2007-04-19
- Construct for LOINC Short Name
- MDCR gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | MDCR 基因 Synonyms: LIS1; |
| es-ES | Spanish (Spain) | Gen MDCR |
| it-IT | Italian (Italy) | MDCR, gene Synonyms: Gene MDCR |
| et-EE | Estonian (Estonia) | MDCR geen |
| tr-TR | Turkish (Turkey) | MDCR geni |
| ru-RU | Russian (Russian Federation) | MDCR ген |
| nl-NL | Dutch (Netherlands) | MDCR-gen Synonyms: MDCR gen |
| el-GR | Greek (Greece) | Γονίδιο MDCR Synonyms: Γονίδιο MDCR |
LOINC Copyright
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