Version 2.78

Description

Anti-fibrillarin antibody (AFA), also known as anti-U3-RNP, is an antibody to a nucleolar ribonucleoprotein called fibrillarin, which marks the site of formation of the nucleolus in cells that are dividing. AFA is associated with systemic sclerosis (scleroderma) and is more prevalent in African American patients with scleroderma compared to other patient populations. In addition, patients with scleroderma who have AFA tend to be younger at disease onset and have a higher frequency of diffuse cutaneous involvement, pulmonary artery hypertension, musculoskeletal and cardiac involvement, and lower frequency of arthritis. PMID: 21572159 Source: Regenstrief LOINC, PMID: 21572159

Basic Part Properties

Part Display Name
Fibrillarin
Part Type
Component (Describes the core component or analyte measured)
Created On
2007-08-23
Construct for LOINC Short Name
Fibrillarin

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP65024-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 核仁纤维蛋白
Synonyms: (核仁)纤维蛋白
fr-CA French (Canada) Fibrillarin
et-EE Estonian (Estonia) Fibrillariin
es-ES Spanish (Spain) Fibrilarina
it-IT Italian (Italy) Fibrillarina
tr-TR Turkish (Turkey) Fibrillarin
ru-RU Russian (Russian Federation) Фибрилларин
nl-NL Dutch (Netherlands) fibrillarine
fr-BE French (Belgium) Fibrillarin