LP65333-4
SLC6A4 gene
Active
Description
The SLC6A4 gene (solute carrier family 6 (neurotransmitter transporter), member 4) [HGNC Gene ID:11050] is located on chromosome 17q11.2. This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008] [NCBI Gene ID:6532] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Name
- SLC6A4 gene
- Part Display Name
- SLC6A4 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2007-09-12
- Construct for LOINC Short Name
- SLC6A4 gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | SLC6A4 基因 Synonyms: 5HTT; |
| et-EE | Estonian (Estonia) | SLC6A4 geen |
| es-ES | Spanish (Spain) | Gen SLC6A4 |
| it-IT | Italian (Italy) | SLC6A4, gene Synonyms: Gene SLC6A4 |
| tr-TR | Turkish (Turkey) | SLC6A4 geni |
| ru-RU | Russian (Russian Federation) | SLC6A4 ген |
| nl-NL | Dutch (Netherlands) | SLC6A4-gen Synonyms: SLC6A4 gen |
| fr-FR | French (France) | SLC6A4 gène |
| el-GR | Greek (Greece) | Γονίδιο SLC6A4 Synonyms: Γονίδιο SLC6A4 |
| pl-PL | Polish (Poland) | SLC6A4 gen Synonyms: Gen SLC6A4 |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://