LP68375-2
CD35
Active
Description
Erythrocyte complement receptor 1 (CR1, also known as CD35, C3b/C4b receptor and immune adherence receptor) is a human gene.
This protein encoded by this gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
CD35
Basic Part Properties
- Part Name
- CD35
- Part Display Name
- CD35
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2008-04-07
- Construct for LOINC Short Name
- CD35
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CD35 |
| fr-CA | French (Canada) | CD35 |
| et-EE | Estonian (Estonia) | CD35 |
| es-ES | Spanish (Spain) | CD35 |
| it-IT | Italian (Italy) | CD35 |
| tr-TR | Turkish (Turkey) | CD35 |
| ru-RU | Russian (Russian Federation) | CD35 |
| nl-NL | Dutch (Netherlands) | CD35 |
| fr-BE | French (Belgium) | CD35 |
| fr-FR | French (France) | CD35 |
| pl-PL | Polish (Poland) | CD35 Synonyms: CD35 |
| el-GR | Greek (Greece) | CD35 Synonyms: CD35 |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://